Personalized Therapy of Prostate Cancer

As prostate cancer is the second leading cause of death after lung cancer, several diagnostic strategies have been introduced in recent years. Among these prostate-specific antigens, it widely recognized that this simplest and most common clinical endpoint - genetic instability part oncogenic process. Gene mutations involved DNA repair mechanisms may promote participate oncogenesis metastatic progression. In abnormalities are primarily due to somatic or constitutional BRCA1/2 genes. Treatment options for currently discussed media by urological associations. Focal therapy expected same oncological efficacy as whole gland with fewer side effects. Accurate diagnosis multiparametric magnetic resonance imaging (MRI). review, we examine various studies described presently molecular targets personalized therapy.